Hand-book of chemistry Volume 18 - Leopold Gmelin, Paperback

• Release Date   5/21/2012
• ISBN-13   9781236350282 | 978-1-236-35028-2
• ISBN   1236350286 | 1-236-35028-6
• Format   Paperback
• Author(s)   Leopold Gmelin
• This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1871 Excerpt: ...The poison contained in the secretion of the cutaneous glands of the salamander.--On older investigations of the poison of toads and salamanders. See l'ii ait. The secretion obtained by scraping the sides of the head and the back of the animal with a teaspoon, is white, viscid, and strongly alkaline. When mixed with water and heated to 59, it deposits white curdy flocks, after removing which, a clear, alkaline, and highly poisonous filtrate is obtained. This is precipitated with phosphomolybdic acid. the resulting white curdy flocks are washed and dissolved in baryta-water. excess of baryta is removed by means of carbonic acid, and the filtrate is concentrated, finally in a retort through which a stream of hydrogen is passed. In this process long needles (of the hydrated base, according to Zalesky) are formed, and afterwards disappear, and ultimately there remains a colourless, brittle, amorphous mass. It contains, besides the poisonous, strongly alkaline samanderine, a resin produced by alteration of that body, which combines with hydrochloric acid, is insoluble in water, but dissolves in alcohol, forming a solution which exhibits a transient greenish fluorescence..... 576........ 100-00........ 100-0........ lOO'O Samanderine is not volatile without decomposition. It retains its poisonous properties for months after drying. Its aqueous solution and an aqueous extract of the secretion of the cutaneous glands likewise retain their activity after prolonged boiling, but probably lose it by gradual drying in the air. Samanderine dissolves in water, forming a strongly alkaline solution. On mixing a strong aqueous solution with hydrochloric acid, it yields slender non-poisonous needles, containing 10-6 p. c. of hydrochloric acid (C(BNSHII00"),2HC1 requires ...